Endocrine Abstracts

Estrogens, in particular 17β-estradiol (E2), orchestrate cellular mechanisms involved in the development and differentiation of various neuron populations, modulation of synaptic plasticity, induction of neuronal survival, and neurogenesis. Beneficial effects of E2 have been widely reported against a variety of insults, including H2O2 injury, serum deprivation, and glutamate excitotoxicity. Recently, we identified E2 ...